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The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment choice for chronic weight management in addition to a reduced-calorie diet and physical exercise.

Using two separate drugs to shed weight can be very effective you'll find combinations as you're watching FDA now awaiting approval. When dealing with weight loss and the people that go through it you ought to err along the side of caution and let the FDA do its job and demand some research be done so that the public knows the side effects and risks of the medications before we take them. Keep in mind that drug companies come in business to generate income and that they would say everything to keep people on his or her medications.

Researchers found that participants using this drug for a year, lost weight within 4 weeks and have kept the weight off during the entire 56 weeks with the study. Contrave is often a combination with the drugs naltrexone and bupropion, which appears to reflect a brand new trend of weight-loss drugs which can be made up of many active ingredient, that might make them more effective and safer.

Combo-pilling may be the newest fad or even better the newest in the future under scrutiny and for that reason it is just more publicly known although in the past, comb-pilling to lose weight has been around since the eighties. The biggest reason that by using a combination of pills is now popular could be the fact that by right now there aren't long term prescription weightloss pills that have been licensed by the FDA apart from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications even though some of the combinations are actually rejected or have yet to be authorized by the FDA.

Seizures certainly are a side effect with Contrave and shouldn't be taken in those with seizure disorders. The drug could also raise hypertension and heartrate, and must not be used in those with a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy using the drug.

The FDA also warned that Contrave can raise blood pressure levels and pulse rate and must 't be used in patients with uncontrolled high blood pressure levels, as well as by you aren't heart-related and cerebrovascular (circulation dysfunction impacting mental performance) disease. Patients using a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes having a boxed warning to alert physicians and patients towards the increased likelihood of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for smoking cessation.

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