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  • On September 26, UCLA researcher reported the outcome of a study, which indicated that Asians who're struggling with alcoholism may benefit especially from naltrexone, considered one of three medications licensed by the U.S. Food and Drug Administration (FDA) for your treatment of alcoholism. Recent research has found out that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent have a particular mutation that creates them prone to benefit from naltrexone, compared with about 20% of Caucasians and less than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director with the UCLA Addictions Laboratory. The findings are currently available online ( inside journal Neuropsychopharmacology and will be published in an upcoming print edition in the journal.

    Using two separate drugs to lose weight can be very effective you can find combinations as you're watching FDA now awaiting approval. When dealing with weight loss and the those who go through it you should err to the side of caution and let the FDA do its job and demand some research be done so your public knows the side effects and risks of the medications before we drive them. Keep in mind that drug companies come in business to generate income and that they would say almost anything to keep people on his or her medications.

    Researchers found that participants investing in this drug to get a year, lost weight within four weeks and have kept the weight off through the 56 weeks with the study. Contrave is a combination of the drugs naltrexone and bupropion, which appears to reflect a whole new trend of weight-loss drugs that are made up of many active ingredient, which might make them more effective and safer.

    Combo-pilling will be the newest fad or also the newest ahead under scrutiny and thus it is just more publicly known in recent months, comb-pilling for losing weight has been around since the eighties. The biggest reason that utilizing a combination of pills is now popular may be the fact that as of right now there are not any long term prescription weight loss supplements that have been approved by the FDA aside from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications however some of the combinations are already rejected or have yet to be authorized by the FDA.

    Seizures really are a side effect with Contrave and shouldn't be taken in those with seizure disorders. The drug also can raise hypertension and heart rate, and must not be used in people who have a history of heart attack or stroke in the earlier six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with all the drug.

    The FDA also warned that Contrave can raise blood pressure and pulse rate and must not be used in patients with uncontrolled high blood pressure, along with by a person with heart-related and cerebrovascular (blood vessel dysfunction impacting your brain) disease. Patients using a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes using a boxed warning to alert physicians and patients to the increased chance of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for quitting smoking.

    Approving a drug using this many potentially lethal negative effects is inconsistent with the mission statement in the FDA. The power in the drug manufacturing lobby is blatantly evident within the approval of many drugs requiring 'post-marketing' studies which might be clearly significant to overall drug safety inside US.

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